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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A1
All Species:
5.76
Human Site:
S142
Identified Species:
12.67
UniProt:
P41440
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41440
NP_919231.1
591
64868
S142
A
Y
S
S
Y
I
F
S
L
V
R
P
A
R
Y
Chimpanzee
Pan troglodytes
XP_001157360
590
64733
S142
A
Y
S
S
Y
I
F
S
L
V
R
P
A
R
Y
Rhesus Macaque
Macaca mulatta
XP_001118114
475
51869
P50
P
G
E
S
F
I
T
P
Y
L
L
G
P
D
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P41438
512
58132
Y87
P
V
F
L
L
T
D
Y
L
R
Y
K
P
V
L
Rat
Rattus norvegicus
Q62866
512
58076
Y87
P
I
F
L
L
T
D
Y
L
R
Y
K
P
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521689
430
48416
Chicken
Gallus gallus
NP_001006513
496
55568
V71
H
D
K
N
F
T
Q
V
E
V
T
N
E
I
T
Frog
Xenopus laevis
NP_001085999
531
60307
R106
S
T
E
R
N
F
T
R
E
Q
V
T
N
E
I
Zebra Danio
Brachydanio rerio
XP_002662447
528
59393
Y103
N
P
V
L
S
Y
S
Y
M
V
V
L
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
F107
T
M
M
K
L
M
Q
F
M
Y
A
F
A
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
73.2
N.A.
N.A.
59.3
58.8
N.A.
47.3
53.4
51.4
52.1
N.A.
N.A.
N.A.
26.3
34.6
Protein Similarity:
100
99.1
74.7
N.A.
N.A.
68.5
68.1
N.A.
59
64.4
63.9
63.9
N.A.
N.A.
N.A.
40
51.4
P-Site Identity:
100
100
13.3
N.A.
N.A.
6.6
6.6
N.A.
0
6.6
0
6.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
26.6
N.A.
N.A.
6.6
6.6
N.A.
0
20
6.6
13.3
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
0
10
0
28
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
19
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
19
0
0
0
0
0
19
0
0
0
10
10
0
% E
% Phe:
0
0
19
0
19
10
19
10
0
0
0
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
28
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
0
19
0
0
10
% K
% Leu:
0
0
0
28
28
0
0
0
37
10
10
10
0
0
19
% L
% Met:
0
10
10
0
0
10
0
0
19
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
10
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
28
10
0
0
0
0
0
10
0
0
0
19
28
10
0
% P
% Gln:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
19
19
0
0
19
0
% R
% Ser:
10
0
19
28
10
0
10
19
0
0
0
0
0
0
10
% S
% Thr:
10
10
0
0
0
28
19
0
0
0
10
10
0
10
10
% T
% Val:
0
10
10
0
0
0
0
10
0
37
19
0
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
19
10
0
28
10
10
19
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _